SCHEMBL13617608

SCHEMBL13617608

Cc1ccc(C(C)(c2ccc(O)c(C)c2)c2ccc(O)c(C)c2)cc1C

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 15/20 0.71
ESR2 Q92731 7/20 0.71
AR P10275 3/20 0.55
TDP1 Q9NUW8 2/20 0.48
TP53 P04637 1/20 0.48
ALDH1A1 P00352 3/20 0.47
GAA P10253 2/20 0.47
PKM P14618 2/20 0.47
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PDE10A Q9Y233 1/20 0.45
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217305 0.93 ESR1 (0.80) ESR1ESR2ARTDP1TP53
SCHEMBL29465776 0.93 ESR1 (0.80) ESR1ESR2ARTDP1TP53
SCHEMBL29471727 0.93 ESR1 (0.80) ESR1ESR2ARTDP1TP53
SCHEMBL12299315 0.91 ESR1 (0.71) ESR1ESR2ARTDP1TP53
SCHEMBL9298912 0.89 ESR1 (0.74) ESR1ESR2ARTDP1TP53
SCHEMBL13241748 0.87 ESR1 (0.87) ESR1ESR2ARTDP1TP53
SCHEMBL31463334 0.87 ESR1 (0.71) ESR1ESR2ARTDP1TP53
SCHEMBL7915978 0.85 ESR1 (0.81) ESR1ESR2ARTDP1TP53
SCHEMBL5031065 0.85 ESR1 (0.75) ESR1ESR2ARTDP1TP53
SCHEMBL10774275 0.85 ESR1 (0.75) ESR1ESR2ARTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009133456-A1 SPIN-ON GRADED K SILICON ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-11-05 WO disclosed