Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.81 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.81 |
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298912 | 0.91 | ESR1 (0.74) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL217305 | 0.91 | ESR1 (0.80) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL29465776 | 0.91 | ESR1 (0.80) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL29471727 | 0.91 | ESR1 (0.80) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL29720626 | 0.90 | ESR1 (1.00) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL835556 | 0.90 | ESR1 (1.00) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL697802 | 0.88 | ESR1 (0.83) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL29696059 | 0.88 | ESR1 (0.83) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL13617608 | 0.85 | ESR1 (0.71) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL31463334 | 0.85 | ESR1 (0.71) | ESR1ESR2ARTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514334-A | Polyphenolic compounds | GENERAL ELECTRIC COMPANY (US) | 1985-04-30 | — | — | US | claimed |
| US-6222004-B1 | MOLDABILITY IN BLOW MOLDING; APPEARANCE AND COLOR TONE | IDEMITSU PETROCHEMICAL CO., LTD (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-1035151-A1 | BRANCHED POLYCARBONATE RESIN | Idemitsu Petrochemical Co., Ltd. (JP) | 2000-09-13 | — | — | EP | disclosed |
| US-4514334-A | Polyphenolic compounds | GENERAL ELECTRIC COMPANY (US) | 1985-04-30 | — | — | US | disclosed |