Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 17/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 14/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13892884 | 0.95 | ADRB1 (0.65) | ADRB1ADRB2ADRB3DRD2DRD1 | |
| SCHEMBL13892808 | 0.88 | ADRB2 (0.60) | ADRB1ADRB2ADRB3DRD2DRD1 | |
| SCHEMBL13618087 | 0.88 | ADRB2 (0.69) | ADRB1ADRB2ADRB3 | |
| SCHEMBL13617399 | 0.88 | ADRB2 (0.68) | ADRB1ADRB2ADRB3 | |
| SCHEMBL13617395 | 0.83 | ADRB2 (0.79) | ADRB1ADRB2ADRB3DRD2DRD1 | |
| SCHEMBL13617474 | 0.83 | ADRB2 (0.78) | ADRB1ADRB2ADRB3DRD2DRD1 | |
| SCHEMBL3837614 | 0.80 | ADRB2 (0.84) | ADRB1ADRB2ADRB3 | |
| SCHEMBL3838763 | 0.80 | ADRB2 (0.84) | ADRB1ADRB2ADRB3 | |
| SCHEMBL3837617 | 0.80 | ADRB2 (0.84) | ADRB1ADRB2ADRB3 | |
| SCHEMBL3838557 | 0.79 | ADRB2 (0.85) | ADRB1ADRB2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641465-B1 | COMBINATIONS OF AN ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONIST AND A CORTICOSTEROID | THERAVANCE INC (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1446379-B1 | ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2009-04-29 | — | — | EP | disclosed |