SCHEMBL13618142

SCHEMBL13618142

CC(C)(C)c1ccc2c(c1)ncn2-c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 14/20 0.65
HTT P42858 1/20 0.57
KDR P35968 1/20 0.55
SRC P12931 2/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19467894 0.88 GABRA1 (0.63) FGFR1HTTSRC
SCHEMBL19915930 0.86 FGFR1 (0.62) FGFR1HTTKDRSRCALDH1A1
SCHEMBL2189538 0.84 HPGD (0.52) FGFR1ALDH1A1
SCHEMBL31320827 0.83 HPGD (0.56) FGFR1KDRALDH1A1
SCHEMBL13871735 0.81 HTT (0.66) FGFR1HTT
SCHEMBL2646079 0.79 HPGD (0.47) FGFR1ALDH1A1
SCHEMBL31261227 0.79 FGFR1 (0.66) FGFR1SRCALDH1A1
SCHEMBL7986978 0.79 FGFR1 (1.00) FGFR1HTTKDRSRC
SCHEMBL12415689 0.78 GABRA1 (0.58) FGFR1KDR
SCHEMBL2646141 0.78 GABRA1 (0.57) FGFR1KDRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192668-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192668-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-8481733-B2 Substituted imidazopyr- and imidazotri-azines OSI Pharmaceuticals, LLC (US) 2013-07-09 US disclosed
US-8481733-B2 Substituted imidazopyr- and imidazotri-azines OSI Pharmaceuticals, LLC (US) 2013-07-09 US disclosed
US-20090286768-A1 SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES OSI PHARMACEUTICALS, INC. (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192668-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF XPO4, OR10J3, EPB41 FGFR1 3775/4885HTT 4174/4885KDR 2584/4885
US-20090286768-A1 SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES ABL1, TPMT, CYP2C19 FGFR1 163/4885HTT 513/4885KDR 1730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.