Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136373 | 0.91 | — | — | |
| SCHEMBL17996661 | 0.91 | — | — | |
| SCHEMBL9136376 | 0.91 | — | — | |
| SCHEMBL30924778 | 0.80 | LMNA (0.47) | ALDH1A1LMNATSHRHSD17B10MEN1 | |
| SCHEMBL16938660 | 0.78 | TSHR (0.40) | TSHRCYP4F2CYP4A11HSD17B10MGAM | |
| SCHEMBL27817000 | 0.78 | OXER1 (0.45) | TSHRCYP4F2CYP4A11HSD17B10MGAM | |
| SCHEMBL27746821 | 0.78 | TSHR (0.40) | TSHRCYP4F2CYP4A11HSD17B10MGAM | |
| SCHEMBL869080 | 0.77 | TSHR (0.53) | ALDH1A1LMNATSHRCYP4F2CYP4A11 | |
| SCHEMBL821076 | 0.77 | TSHR (0.53) | ALDH1A1LMNATSHRCYP4F2CYP4A11 | |
| SCHEMBL869082 | 0.77 | TSHR (0.53) | ALDH1A1LMNATSHRCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |