Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071897 | 0.85 | KDM4E (0.36) | CNR1CNR2KDM4EMEN1KMT2A | |
| SCHEMBL1518881 | 0.84 | KDM4E (0.38) | CNR1CNR2KDM4EMEN1KMT2A | |
| SCHEMBL8265459 | 0.81 | KDM4E (0.35) | CNR1CNR2KDM4EMEN1KMT2A | |
| SCHEMBL12642807 | 0.79 | KDM4E (0.38) | CNR1CNR2KDM4EMEN1KMT2A | |
| SCHEMBL663208 | 0.78 | KDM4E (0.37) | KDM4EMEN1KMT2AGAAHTT | |
| SCHEMBL1518257 | 0.78 | CNR1 (0.39) | CNR1CNR2KDM4EMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL5134889 | 0.77 | MEN1 (0.36) | KDM4EMEN1KMT2AGAAHTT | |
| SCHEMBL1083131 | 0.75 | ALDH1A1 (0.39) | CNR1CNR2KDM4EMEN1KMT2A | |
| SCHEMBL1518420 | 0.75 | ALDH1A1 (0.42) | CNR1CNR2KDM4EMEN1KMT2A | |
| SCHEMBL1518646 | 0.75 | MEN1 (0.37) | CNR1CNR2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |