Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.66 |
| ▸ | PDE5A | O76074 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4478716 | 0.95 | F2RL3 (0.60) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4483522 | 0.90 | CYP1A2 (0.56) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3621787 | 0.89 | ALDH1A1 (0.67) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27669280 | 0.89 | F2RL3 (0.55) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3840013 | 0.88 | MAPT (0.57) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4478119 | 0.87 | CNR2 (0.59) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4028940 | 0.85 | ESR1 (0.69) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28982383 | 0.85 | ALDH1A1 (0.71) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3082745 | 0.84 | F2RL3 (0.61) | F2RL3PDE5AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3843948 | 0.84 | F2RL3 (0.53) | F2RL3PDE5AALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425011-B1 | ENHANCEMENT OF LEARNING AND MEMORY AND TREATMENT OF AMNESIA | CARLSBAD TECHNOLOGY INC (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1331223-B1 | Method of treating sepsis | YUNG SHIN PHARMACEUTICAL IND (TW) | 2008-02-13 | — | — | EP | disclosed |