Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4478716 | 0.88 | F2RL3 (0.60) | F2RL3LMNAP2RX4KMT2AALDH1A1 | |
| SCHEMBL13618343 | 0.84 | F2RL3 (0.66) | F2RL3LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL4483522 | 0.83 | CYP1A2 (0.56) | F2RL3LMNAP2RX4KMT2AMEN1 | |
| SCHEMBL14290280 | 0.82 | RAB9A (0.53) | LMNAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27669280 | 0.82 | F2RL3 (0.55) | F2RL3LMNAP2RX4KMT2AALDH1A1 | |
| SCHEMBL4478119 | 0.80 | CNR2 (0.59) | F2RL3LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3840013 | 0.76 | MAPT (0.57) | F2RL3LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL20379747 | 0.76 | L3MBTL1 (0.71) | LMNAP2RX4KMT2AMEN1ALDH1A1 | |
| SCHEMBL5443540 | 0.76 | CNR2 (0.55) | LMNAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28429765 | 0.75 | MCL1 (0.65) | LMNAKMT2AMAPTSMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425011-B1 | ENHANCEMENT OF LEARNING AND MEMORY AND TREATMENT OF AMNESIA | CARLSBAD TECHNOLOGY INC (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1425011-B1 | ENHANCEMENT OF LEARNING AND MEMORY AND TREATMENT OF AMNESIA | CARLSBAD TECHNOLOGY INC (US) | 2009-11-04 | — | — | EP | disclosed |
| US-7049334-B2 | Enhancement of learning and memory and treatment of amnesia | CARLSBAD TECHNOLOGY, INC. (US) | 2006-05-23 | — | — | US | disclosed |
| CN-1254241-C | Use of fused ring pyrazole compounds for the preparation of medicaments for enhancing learning and memory and for the treatment of amnesia | CARLSBAD TECHNOLOGY INC (US) | 2006-05-03 | — | — | CN | disclosed |
| CN-1585637-A | Enhancement of learning and memory and treatment of amnesia | CARLSBAD TECHNOLOGY INC (US) | 2005-02-23 | — | — | CN | disclosed |
| US-20030105149-A1 | Enhancement of learning and memory and treatment of amnesia | CARLSBAD TECHNOLOGY, INC. | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105149-A1 | Enhancement of learning and memory and treatment of amnesia | NR1H3, NR1H2, RORA | F2RL3 766/4885LMNA 3592/4885P2RX4 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.