Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TYK2 | P29597 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618526 | 0.92 | FFAR1 (0.74) | FFAR1HPGDSMN1; SMN2NR1H4NPC1 | |
| SCHEMBL12284610 | 0.87 | FFAR1 (0.75) | FFAR1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2119500 | 0.86 | FFAR1 (0.66) | FFAR1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6381563 | 0.85 | ALOX15 (0.70) | FFAR1HPGDSMN1; SMN2NR1H4NPC1 | |
| SCHEMBL13814819 | 0.84 | SMN1; SMN2 (0.64) | FFAR1HPGDSMN1; SMN2NR1H4NPC1 | |
| SCHEMBL13814814 | 0.84 | MEN1 (0.63) | FFAR1SMN1; SMN2NR1H4MEN1ALDH1A1 | |
| SCHEMBL3045865 | 0.84 | NR1H4 (0.54) | FFAR1SMN1; SMN2NR1H4ALDH1A1HDAC3 | |
| SCHEMBL7636114 | 0.83 | MAPT (0.61) | SMN1; SMN2NR1H4NPC1RAB9AMEN1 | |
| SCHEMBL13593332 | 0.83 | NR1H4 (0.54) | FFAR1SMN1; SMN2NR1H4NPC1RAB9A | |
| SCHEMBL13593538 | 0.82 | SMN1; SMN2 (0.55) | FFAR1SMN1; SMN2NR1H4ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409569-B1 | Method for administering GLP-1 molecules | EMISPHERE TECH INC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-9370492-B2 | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers | EMISPHERE TECHNOLOGIES, INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-20090281064-A1 | SOLID PHARMACEUTICAL DOSAGE FORMS COMPRISING BISPHOSPHONATES AND MODIFIED AMINO ACID CARRIERS | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281064-A1 | SOLID PHARMACEUTICAL DOSAGE FORMS COMPRISING BISPHOSPHONATES AND MODIFIED AMINO ACID CARRIERS | SLC1A5, SLC7A5, SLC7A1 | FFAR1 664/4885HPGD 1445/4885SMN1; SMN2 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.