Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656684 | 0.95 | MAPT (0.55) | NR1H4ABCB1ABCG2PTGS1HDAC3 | |
| SCHEMBL31661665 | 0.95 | MAPT (0.55) | NR1H4ABCB1ABCG2PTGS1HDAC3 | |
| SCHEMBL27541341 | 0.92 | PTGS1 (0.56) | NR1H4ABCB1ABCG2PTGS1SMN1; SMN2 | |
| SCHEMBL5655206 | 0.87 | HDAC1 (0.62) | ABCB1ABCG2PTGS1HDAC3HDAC4 | |
| SCHEMBL6381563 | 0.85 | ALOX15 (0.70) | NR1H4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13814819 | 0.84 | SMN1; SMN2 (0.64) | NR1H4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13618529 | 0.84 | FFAR1 (0.71) | NR1H4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13814814 | 0.84 | MEN1 (0.63) | NR1H4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5853912 | 0.83 | FFAR1 (0.69) | NR1H4ABCB1ABCG2PTGS1SMN1; SMN2 | |
| SCHEMBL28134734 | 0.83 | ABCB1 (0.53) | ABCB1ABCG2PTGS1SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9370492-B2 | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers | EMISPHERE TECHNOLOGIES, INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-7744910-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-20090281064-A1 | SOLID PHARMACEUTICAL DOSAGE FORMS COMPRISING BISPHOSPHONATES AND MODIFIED AMINO ACID CARRIERS | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-11-12 | — | — | US | disclosed |
| CN-1313439-C | Compounds and compositions for delivery of active agents | EMISPHERE TECH INC (US) | 2007-05-02 | — | — | CN | disclosed |
| US-7186414-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC (US) | 2007-03-06 | — | — | US | disclosed |
| US-20070049557-A1 | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers | EMISPHERE TECHNOLOGIES, INC. | 2007-03-01 | — | — | US | disclosed |
| US-20070049557-A1 | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers | EMISPHERE TECHNOLOGIES, INC. | 2007-03-01 | — | — | US | disclosed |
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| EP-1676832-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-6991798-B1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-12-08 | — | — | US | disclosed |
| CN-1315936-A | Compounds and compositions for delivery of active agents | EMISPHERE TECH INC (US) | 2001-10-03 | — | — | CN | disclosed |
| EP-1102742-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000007979-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281064-A1 | SOLID PHARMACEUTICAL DOSAGE FORMS COMPRISING BISPHOSPHONATES AND MODIFIED AMINO ACID CARRIERS | SLC1A5, SLC7A5, SLC7A1 | NR1H4 663/4885ABCB1 152/4885ABCG2 154/4885 |
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SERPINB1, ELANE, MMP8 | NR1H4 836/4885ABCB1 153/4885ABCG2 69/4885 |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | NR1H4 836/4885ABCB1 153/4885ABCG2 69/4885 |
| US-20070049557-A1 | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers | SLC1A5, SLC7A5, SLC7A1 | NR1H4 682/4885ABCB1 153/4885ABCG2 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.