Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292520 | 0.81 | MAPT (0.46) | PABPC1PIM1BCHEACHECYP1A2 | |
| SCHEMBL9259549 | 0.79 | HTR2A (0.44) | PABPC1L3MBTL1KMT2A | |
| SCHEMBL24753891 | 0.76 | BCHE (0.69) | BCHEACHECYP1A2ALDH1A1KDM4E | |
| SCHEMBL31268135 | 0.76 | BCHE (0.69) | BCHEACHECYP1A2ALDH1A1KDM4E | |
| SCHEMBL7511365 | 0.72 | ALDH1A1 (0.51) | PABPC1BCHEACHECYP1A2ALDH1A1 | |
| SCHEMBL7515373 | 0.71 | KMT2A (0.51) | PABPC1BCHEACHECYP1A2ALDH1A1 | |
| SCHEMBL30763626 | 0.71 | KMT2A (0.51) | PABPC1BCHEACHECYP1A2ALDH1A1 | |
| SCHEMBL11235412 | 0.71 | ALDH1A1 (0.43) | PIM1BCHEACHECYP1A2ALDH1A1 | |
| SCHEMBL7512405 | 0.70 | KMT2A (0.54) | BCHEACHECYP1A2ALDH1A1KDM4E | |
| SCHEMBL29639171 | 0.70 | RAB9A (0.48) | PIM1ACHEALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140467-A1 | OXOBENZINDOLIZINOQUINOLINES AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2009-11-19 | — | — | WO | disclosed |