SCHEMBL13618629

SCHEMBL13618629

CNC(=O)Nc1ccc(Cc2ccc(NC(=O)Nc3ccc(C)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SAE1 Q9UBE0 3/20 0.64
UBA2 Q9UBT2 3/20 0.64
NPC1 O15118 4/20 0.62
ALDH1A1 P00352 3/20 0.55
POLB P06746 2/20 0.54
RAB9A P51151 4/20 0.54
CCNC P24863 1/20 0.54
CDK8 P49336 1/20 0.54
MAPT P10636 2/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
MEN1 O00255 1/20 0.53
TP53 P04637 1/20 0.53
HPGD P15428 1/20 0.53
KMT2A Q03164 1/20 0.53
PTPN7 P35236 1/20 0.51
CNR1 P21554 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13032399 1.00 SAE1 (0.64) SAE1UBA2NPC1ALDH1A1POLB
SCHEMBL14583063 0.98 NPC1 (0.64) SAE1UBA2NPC1ALDH1A1POLB
SCHEMBL12711073 0.94 SAE1 (0.70) SAE1UBA2NPC1ALDH1A1POLB
SCHEMBL13032417 0.91 SAE1 (0.63) SAE1UBA2NPC1ALDH1A1POLB
SCHEMBL821704 0.91 SAE1 (0.65) SAE1UBA2NPC1ALDH1A1POLB
SCHEMBL16556378 0.91 ALDH1A1 (0.64) NPC1ALDH1A1POLBRAB9AMAPT
SCHEMBL16256539 0.89 SAE1 (0.64) SAE1UBA2NPC1ALDH1A1POLB
SCHEMBL172125 0.89 ALDH1A1 (0.67) NPC1ALDH1A1POLBRAB9AMAPT
SCHEMBL13104425 0.88 SAE1 (0.71) SAE1UBA2NPC1ALDH1A1RAB9A
SCHEMBL13411439 0.86 SAE1 (0.50) SAE1UBA2NPC1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090279925-A1 BELT FOR IMAGE FORMING APPARATUS NITTA CORPORATION (JP) 2009-11-12 US disclosed