SCHEMBL821704

SCHEMBL821704

CNC(=O)Nc1ccc(Cc2ccc(NC(=O)NC)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SAE1 Q9UBE0 3/20 0.65
UBA2 Q9UBT2 3/20 0.65
ALDH1A1 P00352 3/20 0.64
KMT2A Q03164 4/20 0.56
TSHR P16473 1/20 0.55
POLB P06746 3/20 0.53
MEN1 O00255 2/20 0.53
LMNA P02545 1/20 0.53
CCNC P24863 1/20 0.53
CDK8 P49336 1/20 0.53
NPC1 O15118 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52
MAPT P10636 1/20 0.51
RAB9A P51151 2/20 0.50
RECQL P46063 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18814513 0.92 TSHR (0.67) SAE1UBA2ALDH1A1KMT2ATSHR
SCHEMBL14583063 0.92 NPC1 (0.64) SAE1UBA2ALDH1A1KMT2APOLB
SCHEMBL21504845 0.92 CA1 (0.57) SAE1UBA2ALDH1A1KMT2ATSHR
SCHEMBL13032399 0.91 SAE1 (0.64) SAE1UBA2ALDH1A1KMT2APOLB
SCHEMBL13618629 0.91 SAE1 (0.64) SAE1UBA2ALDH1A1KMT2APOLB
SCHEMBL10155599 0.89 ALDH1A1 (0.78) SAE1UBA2ALDH1A1KMT2ATSHR
SCHEMBL7472737 0.88 ALDH1A1 (0.60) SAE1UBA2ALDH1A1KMT2ATSHR
SCHEMBL16919653 0.88 ALDH1A1 (0.60) SAE1UBA2ALDH1A1KMT2ATSHR
SCHEMBL8324298 0.88 RAB9A (0.66) SAE1UBA2ALDH1A1KMT2APOLB
SCHEMBL8919908 0.86 ALDH1A1 (0.58) SAE1UBA2ALDH1A1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11713431-B2 Method of making a grease thickener and the thickener made by the method DOW GLOBAL TECHNOLOGIES LLC (US) 2023-08-01 US disclosed
US-11359157-B2 Method of making a grease thickener and the thickener made by the method DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
US-20210324289-A1 METHOD OF MAKING A GREASE THICKENER AND THE THICKENER MADE BY THE METHOD DOW GLOBAL TECHNOLOGIES LLC 2021-10-21 US disclosed
US-10030138-B2 High thermal conductivity thermoplastic resin composition with excellent injection moldability KANEKA CORPORATION (JP) 2018-07-24 US disclosed
EP-2050790-B1 BIODEGRADABLE RESIN COMPOSITION AND MOLDED BODY THEREOF KANEKA CORP (JP) 2018-06-13 EP disclosed
US-20170369809-A1 SYNERGISTIC RUST INHIBITOR COMBINATION FOR LUBRICATING GREASE LUBRIZOL CORP (US) 2017-12-28 US disclosed
US-20160152823-A1 HIGH THERMAL CONDUCTIVITY THERMOPLASTIC RESIN COMPOSITION WITH EXCELLENT INJECTION MOLDABILITY KANEKA CORPORATION (JP) 2016-06-02 US disclosed
EP-3018172-A1 HIGH THERMAL CONDUCTIVITY THERMOPLASTIC RESIN COMPOSITION WITH EXCELLENT INJECTION MOLDABILITY Kaneka Corporation (JP) 2016-05-11 EP disclosed
US-20150337092-A1 COMPOSITE FILMS AND METHODS FOR THEIR PRODUCTION EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-11-26 US disclosed
EP-1881036-B1 BIODEGRADABLE RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED FROM THE SAME KANEKA CORP (JP) 2015-04-15 EP disclosed
US-20110027565-A1 HIGHLY THERMALLY CONDUCTIVE RESIN MOLDED ARTICLE KANEKA CORPORATION (JP) 2011-02-03 US disclosed
EP-1881035-B1 BIODEGRADABLE RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED FROM THE SAME KANEKA CORP (JP) 2010-09-08 EP disclosed
US-20100041791-A1 BIODEGRADABLE RESIN COMPOSITION AND MOLDED ARTICLE OF THE SAME KANEKA CORPORATION (JP) 2010-02-18 US disclosed
US-20090111921-A1 Biodegradable Resin Composition and Molded Article Produced From The Same KANEKA CORPORATION (JP) 2009-04-30 US disclosed
EP-2050790-A1 BIODEGRADABLE RESIN COMPOSITION AND MOLDED BODY THEREOF Kaneka Corporation (JP) 2009-04-22 EP disclosed
US-20090076191-A1 BIODEGRADABLE RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED FROM THE SAME KANEKA CORPORATION (JP) 2009-03-19 US disclosed
US-20080033077-A1 Biodegradable Resin Compositions and Molded Objects Thereof KANEKA CORPORATION (JP) 2008-02-07 US disclosed
EP-1881036-A1 BIODEGRADABLE RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED FROM THE SAME Kaneka Corporation (JP) 2008-01-23 EP disclosed
EP-1881035-A1 BIODEGRADABLE RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED FROM THE SAME Kaneka Corporation (JP) 2008-01-23 EP disclosed
EP-1826241-A1 BIODEGRADABLE RESIN COMPOSITIONS AND MOLDED OBJECTS THEREOF Kaneka Corporation (JP) 2007-08-29 EP disclosed