Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350932 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MAPTMAPK1NPSR1MAPK14 | |
| SCHEMBL10147492 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MAPTMAPK1NPSR1MAPK14 | |
| SCHEMBL13618729 | 0.78 | — | — | |
| SCHEMBL351873 | 0.77 | CNR2 (0.39) | ALDH1A1MAPTMAPK14KDM4EGRN | |
| SCHEMBL10146074 | 0.74 | KDM4E (0.42) | MAPTMAPK14KDM4EGRNSORT1 | |
| SCHEMBL13618716 | 0.71 | KDM4E (0.40) | MAPTMAPK14KDM4EGRNSORT1 | |
| SCHEMBL10147819 | 0.67 | KDM4E (0.42) | MAPTMAPK14KDM4EGRNSORT1 | |
| SCHEMBL351120 | 0.66 | CNR2 (0.51) | MAPTMAPK14KDM4EGRNSORT1 | |
| SCHEMBL12747060 | 0.66 | KDM4E (0.41) | MAPTMAPK14KDM4EGRNSORT1 | |
| SCHEMBL352612 | 0.65 | KDM4E (0.33) | KDM4EGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |