Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618735 | 0.81 | ALDH1A1 (0.51) | GAAMAPK14ALDH1A1MEN1KMT2A | |
| SCHEMBL351648 | 0.80 | CNR2 (0.46) | CNR2MAPTLMNAGAAMAPK14 | |
| SCHEMBL10148017 | 0.79 | CNR2 (0.36) | CNR2MAPTLMNAGAAMAPK14 | |
| SCHEMBL352174 | 0.67 | CNR2 (0.39) | CNR2GAA | |
| SCHEMBL12747057 | 0.66 | ALDH1A1 (0.47) | CNR2GAAMAPK14ALDH1A1NPC1 | |
| SCHEMBL18407336 | 0.66 | ALDH1A1 (0.47) | CNR2MAPK14ALDH1A1POLBRAF1 | |
| SCHEMBL19886210 | 0.64 | ALDH1A1 (0.49) | CNR2MAPTMAPK14ALDH1A1MEN1 | |
| SCHEMBL15121201 | 0.64 | POLB (0.50) | CNR2GAAMAPK14ALDH1A1KMT2A | |
| SCHEMBL18407362 | 0.64 | LMNA (0.55) | LMNAMAPK14ALDH1A1MEN1KMT2A | |
| SCHEMBL15120352 | 0.63 | POLB (0.45) | CNR2LMNAMAPK14ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |