Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882633 | 0.84 | ALDH1A1 (0.51) | KDM4ENPC1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL20687098 | 0.83 | NPC1 (0.43) | KDM4ENPC1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL13722960 | 0.77 | KCNMA1 (0.44) | KDM4ENPC1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL13191549 | 0.77 | KCNMA1 (0.54) | KDM4ENPC1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL12321787 | 0.77 | KMT2A (0.56) | NPC1KMT2ASMN1; SMN2KCNMA1TNKS | |
| SCHEMBL22383440 | 0.75 | NPC1 (0.46) | KDM4ENPC1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL22383444 | 0.74 | NPC1 (0.44) | KDM4ENPC1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL19092972 | 0.74 | KCNMA1 (0.61) | NPC1KMT2ASMN1; SMN2KCNMA1MGAM | |
| SCHEMBL2395074 | 0.74 | KCNMA1 (0.49) | NPC1KMT2ASMN1; SMN2KCNMA1MGAM | |
| SCHEMBL12204565 | 0.74 | SMN1; SMN2 (0.62) | KDM4ENPC1L3MBTL1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143049-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |