Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14447836 | 0.93 | LMNA (0.50) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| SCHEMBL28017667 | 0.93 | LMNA (0.50) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| SCHEMBL12795706 | 0.82 | SMN1; SMN2 (0.42) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| Water SCHEMBL8910642 | 0.81 | SMN1; SMN2 (0.45) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| SCHEMBL2694156 | 0.79 | FABP3 (0.39) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| SCHEMBL14447854 | 0.79 | LMNA (0.47) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| SCHEMBL4657726 | 0.78 | FABP3 (0.53) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| SCHEMBL18971340 | 0.78 | FABP3 (0.53) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| SCHEMBL10337116 | 0.78 | SMN1; SMN2 (0.43) | FABP3SMN1; SMN2LMNAAKT1ESR1 | |
| SCHEMBL25857265 | 0.78 | SMN1; SMN2 (0.46) | FABP3SMN1; SMN2LMNAAKT1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615543-B2 | Complexes with C-reactive protein (CRP) molecules; rheumatoid arthritis, juvenile chronic (rheumatoid) arthritis, ankylosing spondylitis, psoriatic arthritis, systemic vasculitis, polymyalgia rheumatica, Reiter's disease, Crohn's disease and familial Mediterranean fever | PENTRAXIN THERAPEUTICS LIMITED (GB) | 2009-11-10 | — | — | US | disclosed |