SCHEMBL12795706

SCHEMBL12795706

CC(C)OP(=O)(O)OCC[N+](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
FABP3 P05413 1/20 0.40
ADRA1A P35348 2/20 0.39
LMNA P02545 2/20 0.39
AKT1 P31749 2/20 0.39
ESR1 P03372 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
CDC25A P30304 1/20 0.39
AGTR1 P30556 1/20 0.39
KCNH2 Q12809 1/20 0.39
CHRM5 P08912 6/20 0.36
CHRM1 P11229 6/20 0.36
CHRM3 P20309 6/20 0.36
CHRM2 P08172 5/20 0.36
CHRM4 P08173 5/20 0.36
CHRNB2 P17787 4/20 0.36
CHRNA4 P43681 4/20 0.36
CHRNA7 P36544 3/20 0.36
BBOX1 O75936 2/20 0.36
HTR1A P08908 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL8910642 0.87 SMN1; SMN2 (0.45) SMN1; SMN2FABP3ADRA1ALMNAAKT1
SCHEMBL25953332 0.84 BBOX1 (0.34) SMN1; SMN2FABP3BBOX1
SCHEMBL10337116 0.84 SMN1; SMN2 (0.43) SMN1; SMN2FABP3ADRA1ALMNAAKT1
SCHEMBL25857265 0.83 SMN1; SMN2 (0.46) SMN1; SMN2FABP3ADRA1ALMNAAKT1
SCHEMBL2696626 0.82 FABP3 (0.40) SMN1; SMN2FABP3ADRA1ALMNAAKT1
SCHEMBL13619257 0.82 FABP3 (0.40) SMN1; SMN2FABP3ADRA1ALMNAAKT1
SCHEMBL18719364 0.81 SMN1; SMN2 (0.47) SMN1; SMN2FABP3ADRA1ALMNAAKT1
SCHEMBL6130069 0.81 FABP3 (0.39) SMN1; SMN2FABP3ADRA1ALMNAAKT1
SCHEMBL2694156 0.81 FABP3 (0.39) SMN1; SMN2FABP3ADRA1ALMNAAKT1
SCHEMBL6241296 0.81 CA12 (0.36) SMN1; SMN2FABP3ADRA1ALMNAAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209009-A1 PEPTIDES COMPRISING A PHOSPHORYLCHOLINE CONJUGATE AND METHODS OF SYNTHESIZING SAME TARSIER PHARMA LTD. (IL) 2024-06-27 US disclosed
US-11912784-B2 Methods of treating an eye disorder KODIAK SCIENCES INC. (US) 2024-02-27 US disclosed
US-20230382983-A1 COMPLEMENT FACTOR D ANTAGONIST ANTIBODIES AND CONJUGATES THEREOF KODIAK SCIENCES INC. 2023-11-30 US disclosed
US-11584790-B2 Complement factor D antagonist antibodies and conjugates thereof KODIAK SCIENCES INC. (US) 2023-02-21 US disclosed
US-20170190766-A1 ANTIBODIES AND CONJUGATES THEREOF KODIAK SCIENCES INC. 2017-07-06 US disclosed
US-8709465-B2 Diazeniumdiolated phosphorylcholine polymers for nitric oxide release MEDTRONIC VASCULAR, INC. (US) 2014-04-29 US disclosed
US-20110065126-A1 SUBSTANCE-IMMOBILIZING SUBSTRATE, SUBSTANCE-IMMOBILIZED SUBTRATE, AND ANALYSIS METHOD RIKEN (JP) 2011-03-17 US disclosed
US-20100262238-A1 Diazeniumdiolated Phosphorylcholine Polymers for Nitric Oxide Release MEDTRONIC VASCULAR, INC. (US) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170190766-A1 ANTIBODIES AND CONJUGATES THEREOF VEGFA, FLT1, HDGF SMN1; SMN2 3694/4885FABP3 1804/4885ADRA1A 419/4885
US-20230382983-A1 COMPLEMENT FACTOR D ANTAGONIST ANTIBODIES AND CONJUGATES THEREOF CFD, CFH, CFB SMN1; SMN2 3074/4885FABP3 2307/4885ADRA1A 3614/4885
US-20100262238-A1 Diazeniumdiolated Phosphorylcholine Polymers for Nitric Oxide Release NOS1, NOS3, NOS2 SMN1; SMN2 1112/4885FABP3 2244/4885ADRA1A 3445/4885
US-11912784-B2 Methods of treating an eye disorder VEGFA, FLT4, FLT1 SMN1; SMN2 1353/4885FABP3 1447/4885ADRA1A 3596/4885
US-20240209009-A1 PEPTIDES COMPRISING A PHOSPHORYLCHOLINE CONJUGATE AND METHODS OF SYNTHESIZING SAME PTMS, SRMS, SGMS1 SMN1; SMN2 1392/4885FABP3 3462/4885ADRA1A 4359/4885
US-11584790-B2 Complement factor D antagonist antibodies and conjugates thereof CFD, CFH, CFB SMN1; SMN2 3074/4885FABP3 2307/4885ADRA1A 3614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.