Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13619313 | 0.91 | KCNH2 (0.39) | MEN1KMT2AMAPTTP53KDR | |
| SCHEMBL12948674 | 0.90 | DRD2 (0.41) | DHODHMEN1KMT2ADRD2TBXA2R | |
| SCHEMBL12583785 | 0.80 | HDAC3 (0.44) | DHODHMEN1KMT2ADRD2TBXA2R | |
| SCHEMBL12583788 | 0.80 | MEN1 (0.39) | DHODHMEN1KMT2ADRD2TBXA2R | |
| SCHEMBL12948785 | 0.77 | DRD2 (0.45) | MEN1KMT2ADRD2TBXA2RMAPT | |
| SCHEMBL12583782 | 0.73 | KCNH2 (0.55) | DHODHMEN1KMT2AMAPTKDR | |
| SCHEMBL12585200 | 0.71 | PTGER4 (0.51) | HDAC6HDAC3HDAC1HDAC8 | |
| SCHEMBL12585203 | 0.71 | KCNH2 (0.40) | MEN1KMT2AMAPTKDRRAF1 | |
| SCHEMBL988503 | 0.70 | EGFR (0.46) | DRD2TBXA2RMAPTTP53KDR | |
| SCHEMBL12900455 | 0.70 | HDAC3 (0.42) | DHODHMEN1KMT2ADRD2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |