Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13619261 | 0.91 | DHODH (0.39) | POLBMEN1KMT2AHDAC6HDAC3 | |
| SCHEMBL13619317 | 0.89 | ERAP1 (0.39) | POLBMEN1KMT2ANR1H4SMN1; SMN2 | |
| SCHEMBL12948674 | 0.80 | DRD2 (0.41) | MEN1GAAKMT2ANPC1RAB9A | |
| SCHEMBL12585203 | 0.80 | KCNH2 (0.40) | KCNH2POLBMEN1GAAKMT2A | |
| SCHEMBL12585200 | 0.80 | PTGER4 (0.51) | HDAC6HDAC3HDAC1HDAC8 | |
| SCHEMBL12583782 | 0.79 | KCNH2 (0.55) | KCNH2POLBMEN1GAAKMT2A | |
| SCHEMBL13620082 | 0.76 | HDAC1 (0.43) | MEN1KMT2AHDAC6HDAC1NR1H4 | |
| SCHEMBL12583785 | 0.71 | HDAC3 (0.44) | MEN1KMT2AHDAC6HDAC3HDAC1 | |
| SCHEMBL12583788 | 0.71 | MEN1 (0.39) | MEN1GAAKMT2AHDAC6HDAC3 | |
| SCHEMBL12583780 | 0.70 | HSD17B10 (0.46) | MEN1GAAKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |