Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12585307 | 0.91 | MAPT (0.59) | MAPTTP53PTGER4 | |
| SCHEMBL12584542 | 0.90 | MAPT (0.54) | MAPTSMN1; SMN2THRBALDH1A1POLB | |
| SCHEMBL12583920 | 0.86 | MAPT (0.72) | MAPTSMN1; SMN2THRBALDH1A1POLB | |
| SCHEMBL12583929 | 0.85 | MAPT (0.73) | MAPTSMN1; SMN2THRBALDH1A1POLB | |
| SCHEMBL13619447 | 0.83 | MAPT (0.68) | MAPTSMN1; SMN2THRBALDH1A1POLB | |
| SCHEMBL12900450 | 0.83 | F10 (0.54) | MAPTTP53 | |
| SCHEMBL12585763 | 0.81 | PPARG (0.53) | MAPTTP53PTGER4 | |
| SCHEMBL12584030 | 0.80 | MAPT (0.43) | MAPTSMN1; SMN2THRBALDH1A1HTT | |
| SCHEMBL12948790 | 0.79 | P2RX3 (0.46) | MAPTPTGER4 | |
| SCHEMBL12584594 | 0.79 | TP53 (0.45) | MAPTSMN1; SMN2THRBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |