Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.68 |
| ▸ | TP53 | P04637 | 7/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12585311 | 0.91 | TP53 (0.69) | MAPTTP53MEN1ALDH1A1HPGD | |
| SCHEMBL12583932 | 0.85 | MAPT (0.64) | MAPTTP53TSHRL3MBTL1MEN1 | |
| SCHEMBL12900450 | 0.85 | F10 (0.54) | MAPTTP53KMT2A | |
| SCHEMBL23674599 | 0.83 | MAPT (0.82) | MAPTTP53TSHRL3MBTL1MEN1 | |
| SCHEMBL13619299 | 0.83 | MAPT (0.68) | MAPTTP53TSHRALDH1A1THRB | |
| SCHEMBL12948790 | 0.81 | P2RX3 (0.46) | MAPT | |
| SCHEMBL12584141 | 0.79 | PTGER4 (0.48) | MAPTTP53THRB | |
| SCHEMBL13619519 | 0.79 | PTGER4 (0.48) | TP53ALDH1A1 | |
| SCHEMBL12584692 | 0.77 | RAB9A (0.58) | MAPTKMT2ANPSR1 | |
| SCHEMBL12948788 | 0.77 | PTGER4 (0.48) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |