Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486140 | 0.82 | MAPT (0.50) | MAPTGAARAPGEF4ALDH1A1MEN1 | |
| SCHEMBL15227798 | 0.82 | IDO1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL1761294 | 0.79 | MAPT (0.48) | MAPTGAARAPGEF4ALDH1A1MEN1 | |
| SCHEMBL21812073 | 0.73 | THRB (0.38) | MAPTRAPGEF4TSHR | |
| SCHEMBL21283087 | 0.73 | TDP1 (0.38) | RAPGEF4ALDH1A1TSHR | |
| SCHEMBL812374 | 0.73 | — | — | |
| SCHEMBL79108 | 0.73 | — | — | |
| SCHEMBL8033916 | 0.71 | MAPT (0.38) | MAPTGAARAPGEF4ALDH1A1MEN1 | |
| SCHEMBL18593306 | 0.71 | RAPGEF4 (0.47) | MAPTGAARAPGEF4ALDH1A1MEN1 | |
| SCHEMBL9452351 | 0.70 | MEN1 (0.59) | MAPTGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9572881-B2 | Halogenated compounds for photodynamic therapy | NANOQUANTUM SCIENCES, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2009140342-A1 | GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE | SCHERING CORPORATION (US) | 2009-11-19 | — | — | WO | disclosed |