Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987768 | 0.92 | PTGER4 (0.41) | DRD2DRD4CNR2MCHR1PTGER4 | |
| SCHEMBL12584912 | 0.91 | DRD2 (0.39) | DRD2DRD4CNR2PTGER4USP30 | |
| SCHEMBL12584911 | 0.90 | DRD2 (0.40) | DRD2DRD4USP30HTR4NPC1 | |
| SCHEMBL12584739 | 0.89 | CKS1B (0.38) | DRD2DRD4CNR2MCHR1PTGER4 | |
| SCHEMBL12584423 | 0.88 | DRD2 (0.41) | DRD2DRD4CNR2PTGER4USP30 | |
| SCHEMBL13619639 | 0.88 | DRD2 (0.39) | DRD2DRD4USP30HTR4NPC1 | |
| SCHEMBL12584417 | 0.88 | DRD2 (0.41) | DRD2DRD4CNR2USP30HTR4 | |
| SCHEMBL987770 | 0.88 | CYP3A5 (0.36) | DRD2DRD4CNR2MCHR1RORC | |
| SCHEMBL12584239 | 0.88 | MCHR1 (0.38) | DRD2DRD4MCHR1PTGER4HTR4 | |
| SCHEMBL12584935 | 0.88 | CNR2 (0.39) | CNR2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |