Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584911 | 0.92 | DRD2 (0.40) | DRD2DRD4HTR4USP30NPC1 | |
| SCHEMBL12584912 | 0.91 | DRD2 (0.39) | DRD2DRD4HTR4USP30NPC1 | |
| SCHEMBL12584423 | 0.91 | DRD2 (0.41) | DRD2DRD4HTR4USP30NPC1 | |
| SCHEMBL12584417 | 0.90 | DRD2 (0.41) | DRD2DRD4HTR4USP30NPC1 | |
| SCHEMBL13619452 | 0.88 | DRD2 (0.37) | DRD2DRD4HTR4USP30NPC1 | |
| SCHEMBL12585111 | 0.88 | USP30 (0.40) | DRD2DRD4HTR4USP30NPC1 | |
| SCHEMBL986579 | 0.84 | HDAC3 (0.39) | DRD2DRD4USP30NPC1HDAC3 | |
| SCHEMBL12584885 | 0.82 | HDAC3 (0.37) | DRD2DRD4HTR4USP30HDAC3 | |
| SCHEMBL12584999 | 0.82 | HDAC3 (0.37) | DRD2DRD4HTR4USP30HDAC3 | |
| SCHEMBL987915 | 0.82 | HDAC3 (0.38) | DRD2DRD4HTR4USP30HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |