Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497619 | 0.80 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL23941238 | 0.78 | GRM4 (0.30) | GRM4 | |
| SCHEMBL19923615 | 0.77 | GRM4 (0.37) | BRD4GRM4 | |
| SCHEMBL1362914 | 0.76 | — | — | |
| SCHEMBL11625745 | 0.74 | PKM (0.30) | ALDH1A1MAPT | |
| SCHEMBL19923713 | 0.72 | GRM4 (0.33) | GRM4 | |
| SCHEMBL19923460 | 0.72 | GRM4 (0.35) | GRM4 | |
| SCHEMBL19923751 | 0.71 | GRM4 (0.32) | GRM4 | |
| SCHEMBL1363071 | 0.71 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL22702279 | 0.71 | PIK3CD (0.38) | GRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281101-A1 | THERAPEUTIC SUBSTITUTED HYDANTOINS, AND RELATED COMPOUNDS | ALLERGAN, INC. (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281101-A1 | THERAPEUTIC SUBSTITUTED HYDANTOINS, AND RELATED COMPOUNDS | AADAC, ABCG2, SLC10A1 | BRD4 398/4885GRM4 2880/4885CDK9 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.