Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643935 | 0.90 | PTGDR2 (0.43) | KMT2AHTTCNR2CNR1PTGDR2 | |
| SCHEMBL3596003 | 0.86 | ICMT (0.46) | KMT2ACNR2CNR1PTGDR2MYC | |
| SCHEMBL12485507 | 0.82 | KDM4E (0.54) | KMT2AHTTCNR2CNR1PTGDR2 | |
| SCHEMBL1127285 | 0.81 | PLK1 (0.57) | KMT2ACNR2CNR1MEN1ALDH1A1 | |
| SCHEMBL3139926 | 0.80 | PLK1 (0.43) | KMT2AKDM4CCNR2CNR1PTGDR2 | |
| SCHEMBL8355113 | 0.77 | KMT2A (0.63) | KMT2AKDM4CKDM4EMEN1ALDH1A1 | |
| SCHEMBL13619973 | 0.77 | HPGD (0.50) | CNR2CNR1KDM4EALDH1A1 | |
| SCHEMBL8358588 | 0.77 | LMNA (0.62) | KMT2AHTTCNR2CNR1KDM4E | |
| SCHEMBL13518920 | 0.76 | GAA (0.53) | KMT2AKDM4CCNR2CNR1PTGDR2 | |
| SCHEMBL2644030 | 0.76 | CPT1A (0.44) | CNR2CNR1PTGDR2MYCCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134616-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-05 | — | — | WO | disclosed |