Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127428 | 0.91 | ALDH1A1 (0.45) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL1127254 | 0.78 | ALDH1A1 (0.48) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL1127987 | 0.77 | ALDH1A1 (0.49) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL13658301 | 0.76 | KDM4E (0.50) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL1127411 | 0.76 | ALDH1A1 (0.43) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL849144 | 0.74 | MAPK8 (0.50) | ALDH1A1KDM4EHPGDPTGDR2MAPK8 | |
| SCHEMBL4289628 | 0.73 | KDM4E (0.44) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL13658303 | 0.72 | ALDH1A1 (0.44) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL1128142 | 0.72 | KDM4E (0.46) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL1128375 | 0.70 | PTGES (0.48) | ALDH1A1IDO1CYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134616-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-05 | — | — | WO | disclosed |