SCHEMBL13620142

SCHEMBL13620142

Cc1cc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccccc4)cc3)cc2)cc(C)c1-c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
KMT2A Q03164 3/20 0.37
HDAC4 P56524 1/20 0.37
AKR1C4 P17516 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
TSPO P30536 1/20 0.34
RORC P51449 1/20 0.34
APP P05067 1/20 0.33
MYC P01106 1/20 0.33
AVPR1A P37288 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
MAPK8 P45983 1/20 0.32
RCE1 Q9Y256 1/20 0.32
IL1R1 P14778 1/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14755990 0.93 L3MBTL1 (0.42) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL13620371 0.92 KDM4E (0.39) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL13620141 0.92 KDM4E (0.41) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL14755988 0.91 L3MBTL1 (0.43) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL14755993 0.91 L3MBTL1 (0.45) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL13620159 0.91 KDM4E (0.40) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL24949230 0.88 L3MBTL1 (0.52) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL13620160 0.87 TSPO (0.34) KDM4EL3MBTL1ATMKMT2AAKR1C4
SCHEMBL21970864 0.87 KDM4E (0.45) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL18679646 0.87 PTGER4 (0.35) KDM4EL3MBTL1ATMKMT2AAKR1C4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8852758-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-07 US disclosed
US-8852758-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-07 US disclosed
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-8318322-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-27 US disclosed
US-8318322-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-27 US disclosed
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound TYR, PAH, NAT1 KDM4E 1140/4885L3MBTL1 1077/4885ATM 563/4885
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound TYR, PAH, NAT1 KDM4E 1176/4885L3MBTL1 1073/4885ATM 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.