Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 7/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620529 | 0.88 | KMT2A (0.45) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL3493848 | 0.80 | KMT2A (0.55) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL13620530 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL3494013 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL13341339 | 0.78 | ALDH1A1 (0.75) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL3494278 | 0.76 | MAPT (0.58) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL3492677 | 0.76 | MAPT (0.61) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL4519702 | 0.75 | KMT2A (0.61) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL3494338 | 0.75 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL3490694 | 0.75 | MAPT (0.65) | ALDH1A1KMT2AMEN1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123301-A1 | THERAPEUTIC AGENT FOR URINARY TRACT DISEASE | ASKA Pharmaceutical Co., Ltd. (JP) | 2009-11-25 | — | — | EP | disclosed |