Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620440 | 0.88 | ALDH1A1 (0.52) | KMT2AMAPTALDH1A1TDP1MEN1 | |
| SCHEMBL14218882 | 0.80 | MAPT (0.46) | KMT2ARXFP1LMNAKCNH2NPSR1 | |
| SCHEMBL13620316 | 0.80 | KMT2A (0.44) | KMT2ARXFP1LMNAKCNH2NPSR1 | |
| SCHEMBL3492879 | 0.78 | RXFP1 (0.61) | KMT2ARXFP1LMNAKCNH2NPSR1 | |
| SCHEMBL3492256 | 0.74 | KMT2A (0.51) | KMT2ARXFP1LMNAKCNH2NPSR1 | |
| SCHEMBL14650905 | 0.74 | KMT2A (0.53) | KMT2ARXFP1LMNAKCNH2NPSR1 | |
| SCHEMBL3491627 | 0.73 | KMT2A (0.48) | KMT2ARXFP1LMNAKCNH2NPSR1 | |
| SCHEMBL3491528 | 0.73 | KMT2A (0.54) | KMT2ARXFP1LMNAKCNH2NPSR1 | |
| SCHEMBL3493794 | 0.72 | KMT2A (0.59) | KMT2ARXFP1LMNAKCNH2NPSR1 | |
| SCHEMBL3491630 | 0.72 | KMT2A (0.49) | KMT2ARXFP1LMNAKCNH2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123301-A1 | THERAPEUTIC AGENT FOR URINARY TRACT DISEASE | ASKA Pharmaceutical Co., Ltd. (JP) | 2009-11-25 | — | — | EP | disclosed |