Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 18/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620474 | 1.00 | OPRD1 (0.78) | OPRD1OPRM1OPRK1 | |
| SCHEMBL3131262 | 0.88 | OPRD1 (0.79) | OPRD1OPRM1OPRK1 | |
| SCHEMBL14462016 | 0.88 | OPRD1 (0.77) | OPRD1OPRM1OPRK1 | |
| SCHEMBL14462014 | 0.88 | OPRD1 (0.77) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12569777 | 0.88 | OPRD1 (0.77) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12569764 | 0.87 | OPRD1 (0.65) | OPRD1OPRM1OPRK1 | |
| SCHEMBL14360708 | 0.87 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL6796562 | 0.87 | OPRD1 (0.98) | OPRD1OPRM1OPRK1 | |
| SCHEMBL2001758 | 0.86 | OPRD1 (0.64) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12624358 | 0.85 | OPRD1 (0.74) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142587-A1 | METHOD OF TREATING ANXIOUS MAJOR DEPRESSIVE DISORDER | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | WO | disclosed |