Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 15/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14462014 | 1.00 | OPRD1 (0.77) | OPRD1OPRK1OPRM1 | |
| SCHEMBL12569777 | 1.00 | OPRD1 (0.77) | OPRD1OPRK1OPRM1 | |
| SCHEMBL12569764 | 0.90 | OPRD1 (0.65) | OPRD1OPRK1OPRM1 | |
| SCHEMBL2001758 | 0.89 | OPRD1 (0.64) | OPRD1OPRK1OPRM1 | |
| SCHEMBL13620476 | 0.88 | OPRD1 (0.78) | OPRD1OPRK1OPRM1 | |
| SCHEMBL13620474 | 0.88 | OPRD1 (0.78) | OPRD1OPRK1OPRM1 | |
| SCHEMBL5173109 | 0.87 | OPRD1 (0.70) | OPRD1OPRK1OPRM1 | |
| SCHEMBL5175367 | 0.87 | OPRD1 (0.70) | OPRD1OPRK1OPRM1 | |
| SCHEMBL12569745 | 0.87 | OPRD1 (0.77) | OPRD1OPRK1OPRM1 | |
| SCHEMBL5174203 | 0.86 | OPRD1 (0.80) | OPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241764-B2 | 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders | ASTRAZENECA AB (SE) | 2007-07-10 | — | — | US | disclosed |