Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.78 |
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.53 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620662 | 0.88 | EGLN3 (1.00) | EGLN3EGLN1KMT2AALDH1A1HPGD | |
| SCHEMBL13620540 | 0.80 | EGLN3 (0.69) | EGLN3EGLN1 | |
| SCHEMBL13620539 | 0.77 | EGLN1 (0.61) | EGLN3EGLN1 | |
| SCHEMBL1080241 | 0.77 | EGLN3 (1.00) | EGLN3EGLN1 | |
| SCHEMBL1079849 | 0.75 | EGLN3 (0.77) | EGLN3EGLN1 | |
| SCHEMBL1080932 | 0.74 | EGLN3 (0.75) | EGLN3EGLN1 | |
| SCHEMBL1081707 | 0.74 | EGLN3 (0.74) | EGLN3EGLN1KMT2AHTTKDM4E | |
| SCHEMBL1081618 | 0.74 | EGLN3 (0.76) | EGLN3EGLN1KMT2AALDH1A1HPGD | |
| SCHEMBL1080635 | 0.72 | EGLN3 (0.71) | EGLN3EGLN1HTT | |
| SCHEMBL1081805 | 0.70 | EGLN1 (0.69) | EGLN3EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134847-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-11-05 | — | — | WO | disclosed |