Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.61 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620540 | 0.83 | EGLN3 (0.69) | EGLN1EGLN3L3MBTL1APEX1 | |
| SCHEMBL13620538 | 0.77 | EGLN3 (0.78) | EGLN1EGLN3 | |
| SCHEMBL13620662 | 0.76 | EGLN3 (1.00) | EGLN1EGLN3L3MBTL1 | |
| SCHEMBL12172135 | 0.65 | EGLN1 (0.55) | EGLN1 | |
| SCHEMBL1080932 | 0.65 | EGLN3 (0.75) | EGLN1EGLN3 | |
| SCHEMBL13521541 | 0.62 | APEX1 (0.64) | EGLN1L3MBTL1EGFRSRCAPEX1 | |
| SCHEMBL23497943 | 0.62 | MAP2K2 (0.40) | EGLN1EGFRSRC | |
| SCHEMBL27957358 | 0.62 | KDM4C (0.39) | EGLN1 | |
| SCHEMBL31286477 | 0.62 | AKR1C3 (0.40) | EGLN1EGFR | |
| SCHEMBL3520599 | 0.61 | FTO (0.48) | EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134847-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-11-05 | — | — | WO | disclosed |