SCHEMBL13620842

SCHEMBL13620842

CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2ccc(C)cc21

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.77
KMT2A Q03164 4/20 0.77
LMNA P02545 4/20 0.77
MEN1 O00255 3/20 0.77
ALDH1A1 P00352 3/20 0.77
HTT P42858 2/20 0.77
USP2 O75604 2/20 0.77
GSTP1 P09211 1/20 0.65
CYP3A4 P08684 1/20 0.52
FTO Q9C0B1 4/20 0.46
RECQL P46063 2/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46
BLM P54132 1/20 0.46
SMAD3 P84022 1/20 0.46
PRMT1 Q99873 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAOB P27338 2/20 0.44
GAPDH P04406 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20353147 0.92 MAPT (0.78) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL14768996 0.92 MAPT (0.68) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL14768995 0.92 MAPT (0.68) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL14769054 0.91 MAPT (0.89) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL14771617 0.87 MEN1 (0.75) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL14771618 0.87 MEN1 (0.75) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL13620617 0.87 MEN1 (0.75) MAPTKMT2ALMNAMEN1ALDH1A1
Fluorescein Diacetate SCHEMBL31658971 0.87 MAPT (1.00) MAPTKMT2ALMNAMEN1ALDH1A1
Fluorescein Diacetate SCHEMBL29453229 0.87 MAPT (1.00) MAPTKMT2ALMNAMEN1ALDH1A1
Fluorescein Diacetate SCHEMBL29353816 0.87 MAPT (1.00) MAPTKMT2ALMNAMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562823-B1 FUNCTIONALIZED NANOLUC INHIBITORS PROMEGA CORP (US) 2023-02-08 EP disclosed
EP-1204430-B1 CONJUGATES AND METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE FOR TRANSPORTING MOLECULES VIA BIOLOGICAL MEMBRANES SANOFI AVENTIS DEUTSCHLAND (DE) 2009-11-04 EP disclosed