Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GAPDH | P04406 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14771618 | 0.95 | MEN1 (0.75) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL12576106 | 0.93 | MAPT (0.69) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL13620842 | 0.92 | MAPT (0.77) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL14768996 | 0.88 | MAPT (0.68) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL14769054 | 0.87 | MAPT (0.89) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL12639986 | 0.87 | MAPT (0.77) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL20353147 | 0.86 | MAPT (0.78) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL12576109 | 0.82 | MEN1 (0.69) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL13620617 | 0.82 | MEN1 (0.75) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL14771617 | 0.82 | MEN1 (0.75) | MAPTKMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051597-B2 | Fluorescent substrate for detection of enzymatic activity of nitrile-related enzyme | MITSUBISHI RAYON CO., LTD. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20140072990-A1 | FLUORESCENT SUBSTRATE FOR DETECTION OF ENZYMATIC ACTIVITY OF NITRILE-RELATED ENZYME | THE UNIVERSITY OF TOKYO (JP) | 2014-03-13 | — | — | US | disclosed |
| US-20130065263-A1 | FLUORESCENT SUBSTRATE FOR DETECTION OF ENZYMATIC ACTIVITY OF NITRILE-RELATED ENZYME | THE UNIVERSITY OF TOKYO (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065263-A1 | FLUORESCENT SUBSTRATE FOR DETECTION OF ENZYMATIC ACTIVITY OF NITRILE-RELATED ENZYME | DNPH1, NOS1, NAALAD2 | MAPT 3727/4885KMT2A 3773/4885LMNA 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.