Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.47 |
| ▸ | DRD1 | P21728 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 9/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362134 | 1.00 | DRD2 (0.47) | DRD2DRD1HTR1AHSD11B1 | |
| SCHEMBL8363249 | 1.00 | DRD2 (0.47) | DRD2DRD1HTR1AHSD11B1 | |
| SCHEMBL1362132 | 1.00 | DRD2 (0.47) | DRD2DRD1HTR1AHSD11B1 | |
| SCHEMBL4551311 | 0.88 | DRD2 (0.62) | DRD2DRD1HTR1AHSD11B1 | |
| SCHEMBL1360527 | 0.88 | DRD2 (0.62) | DRD2DRD1HTR1AHSD11B1 | |
| SCHEMBL4551313 | 0.88 | DRD2 (0.62) | DRD2DRD1HTR1AHSD11B1 | |
| SCHEMBL8731962 | 0.83 | DRD2 (0.44) | DRD2DRD1HTR1A | |
| SCHEMBL1362677 | 0.80 | DRD2 (0.46) | DRD2DRD1HSD11B1 | |
| SCHEMBL1559611 | 0.80 | DRD2 (0.46) | DRD2DRD1HSD11B1 | |
| SCHEMBL1559613 | 0.80 | DRD2 (0.46) | DRD2DRD1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067410-B2 | Phenolic and catecholic amines and prodrugs thereof | H. LUNDBECK A/S (DK) | 2011-11-29 | — | — | US | disclosed |
| US-8067410-B2 | Phenolic and catecholic amines and prodrugs thereof | H. LUNDBECK A/S (DK) | 2011-11-29 | — | — | US | disclosed |
| US-8067410-B2 | Phenolic and catecholic amines and prodrugs thereof | H. LUNDBECK A/S (DK) | 2011-11-29 | — | — | US | disclosed |
| US-20090325946-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-31 | — | — | US | disclosed |
| US-20090325946-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-31 | — | — | US | disclosed |
| US-20090325946-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-31 | — | — | US | disclosed |
| WO-2009156458-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325946-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | COMT, PNMT, TYR | DRD2 210/4885DRD1 515/4885HTR1A 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.