Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638361 | 1.00 | TSHR (0.35) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL1970857 | 1.00 | TSHR (0.35) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL4317430 | 0.78 | TSHR (0.41) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL4592491 | 0.78 | TSHR (0.41) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL8767264 | 0.75 | HSD17B10 (0.33) | TSHRMAPK1HSD17B10TDP1KMT2A | |
| SCHEMBL27704000 | 0.71 | TSHR (0.38) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL239532 | 0.70 | — | — | |
| SCHEMBL12263601 | 0.70 | — | — | |
| SCHEMBL8767596 | 0.68 | AKR1B1 (0.31) | — | |
| Acetone SCHEMBL9679471 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137916-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF OSELTAMIVIR AND ANALOGS THEREOF | BROCK UNIVERSITY (CA) | 2009-11-19 | — | — | WO | disclosed |