Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592491 | 1.00 | TSHR (0.41) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL1970857 | 0.78 | TSHR (0.35) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL638361 | 0.78 | TSHR (0.35) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL13621985 | 0.78 | TSHR (0.35) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL24008838 | 0.78 | TDP1 (0.40) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL5712812 | 0.71 | TSHR (0.34) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL13997699 | 0.70 | TSHR (0.34) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL27704000 | 0.69 | TSHR (0.38) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL12263601 | 0.67 | — | — | |
| SCHEMBL11303577 | 0.67 | TSHR (0.33) | TSHRMAPK1HSD17B10TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106754590-A | Engineering strain and application thereof for producing DHHA | 上海交通大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106010999-A | Gene engineering strain, culturing method and application of gene engineering strain | 上海交通大学 | 2016-10-12 | — | — | CN | disclosed |
| CN-106010999-A | Gene engineering strain, culturing method and application of gene engineering strain | 上海交通大学 | 2016-10-12 | — | — | CN | disclosed |
| EP-2084519-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | Los Alamos National Security, LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| US-20080311631-A1 | Biosynthetic Production of 4-Amino 4-Deoxychorismate (Adc) and [3R,4R]-4-Amino-3-Hydroxycyclohexa-1,5-Diene-1-Carboxylic Acid (3,4-Cha) | DSM IP ASSETS B. V. (NL) | 2008-12-18 | — | — | US | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |
| EP-1888760-A1 | BIOSYNTHETIC PRODUCTION OF (5S,6S)-6-AMINO-5-HYDROXYCYCLOHEXA-1,3-DIENE-1-CARBOXYLIC ACID (2,3-CHA) | DSM IP ASSETS B.V. (NL) | 2008-02-20 | — | — | EP | disclosed |
| EP-1751297-A2 | BIOSYNTHETIC PRODUCTION OF 4-AMINO-4-DEOXYCHORISMATE (ADC) AND [3,4R]-4-AMINO-3-HYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC ACID (3,4-CHA) | DSMIP Assets B.V. (NL) | 2007-02-14 | — | — | EP | disclosed |
| WO-2006128706-A1 | BIOSYNTHETIC PRODUCTION OF (5S,6S)-6-AMINO-5-HYDROXYCYCLOHEXA-1,3-DIENE-1-CARBOXYLIC ACID (2,3-CHA) | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | disclosed |
| EP-1728872-A1 | Biosynthetic production of (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid (2,3-CHA) | DSM IP Assets B.V. (NL) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005118829-A2 | BIOSYNTHETIC PRODUCTION OF 4-AMINO-4-DEOXYCHORISMATE (ADC) AND [3R,4R]-4-AMINO-3-HYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC ACID (3,4-CHA) | DSM IP ASSETS B.V. (NL) | 2005-12-15 | — | — | WO | disclosed |
| EP-1602730-A2 | Biosynthetic production of 4-amino-4-deoxychorismate (ADC) and [3R,4R]-4-amino-3-hydroxycyclohexa-1,5-diene-1-carboxylic acid (3,4-CHA) | DSM IP Assets B.V. (NL) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311631-A1 | Biosynthetic Production of 4-Amino 4-Deoxychorismate (Adc) and [3R,4R]-4-Amino-3-Hydroxycyclohexa-1,5-Diene-1-Carboxylic Acid (3,4-Cha) | HPD, DHPS, PGD | TSHR 2974/4885MAPK1 3910/4885HSD17B10 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.