Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | ITGAV | P06756 | 4/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661034 | 0.94 | MAPT (0.35) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL2660058 | 0.88 | MAPT (0.39) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL2660586 | 0.88 | MAPT (0.33) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL9072973 | 0.87 | ITGB3 (0.33) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL13221826 | 0.84 | MAPT (0.34) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL2660669 | 0.84 | MAPT (0.34) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL2660338 | 0.83 | MAPT (0.34) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL2659344 | 0.83 | MAPT (0.40) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL13203933 | 0.83 | MAPT (0.34) | MAPTLMNATP53THRBITGB3 | |
| SCHEMBL2661454 | 0.82 | ITGB3 (0.36) | MAPTLMNATP53THRBITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286975-A1 | Indole compound | YASUMA TSUNEO | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286975-A1 | Indole compound | GCKR, GPR119, SLC5A1 | MAPT 4224/4885LMNA 4727/4885TP53 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.