SCHEMBL1362274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16343572	0.83	CSNK2A1 (0.58)	TAAR1CSNK2A1PNMTBACE1
	SCHEMBL11445119	0.81	BACE1 (0.47)	PRKCIBACE1ABL1
	SCHEMBL28329381	0.79	CSNK2A1 (0.46)	TAAR1PRKCICSNK2A1ENPP2PNMT
	SCHEMBL5990056	0.78	HTR7 (0.51)	TAAR1CSNK2A1ENPP2PNMTBACE1
	SCHEMBL10075879	0.77	ABAT (0.52)	TAAR1CSNK2A1ENPP2BACE1
	SCHEMBL12062955	0.76	PRMT6 (0.62)	—
	SCHEMBL14213318	0.76	TAAR1 (0.57)	TAAR1PRKCICSNK2A1ENPP2PNMT
	SCHEMBL1363132	0.76	DPP4 (0.46)	TAAR1PRKCICHRNB4CHRNA3CHRNA7
	SCHEMBL4545273	0.76	FFAR1 (0.56)	FYN
	SCHEMBL10064807	0.76	IKBKB (0.42)	PRKCICALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.