Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PRKCA | P17252 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7151764 | 0.90 | ALDH1A1 (0.67) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL10916570 | 0.85 | ALDH1A1 (0.57) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL2816910 | 0.85 | PRKCA (0.68) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL812728 | 0.85 | PRKCA (0.68) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL2815895 | 0.85 | PRKCA (0.68) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL7154581 | 0.85 | PRKCA (0.68) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL7155714 | 0.85 | PRKCA (0.68) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL13755806 | 0.85 | PRKCA (0.68) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL571244 | 0.84 | TSHR (0.53) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL16217633 | 0.83 | PRKCA (0.67) | ALDH1A1PRKCAADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133401-A1 | SYNTHESIS OF TIMOSAPONIN BII | PHYTOPHARM PLC (GB) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009132478-A1 | SYNTHESIS OF TIMOSAPONIN BII | PHYTOPHARM PLC (GB) | 2009-11-05 | — | — | WO | disclosed |