Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622772 | 0.81 | SLC6A4 (0.31) | — | |
| SCHEMBL1134445 | 0.73 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL1134416 | 0.73 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL11244272 | 0.65 | OPRD1 (0.33) | OPRD1 | |
| SCHEMBL11244277 | 0.65 | OPRD1 (0.33) | OPRD1 | |
| SCHEMBL11244267 | 0.65 | OPRD1 (0.33) | OPRD1 | |
| SCHEMBL13623025 | 0.62 | KDM1A (0.32) | — | |
| SCHEMBL11248125 | 0.61 | OPRD1 (0.32) | OPRD1 | |
| SCHEMBL10521888 | 0.59 | SLC6A12 (0.39) | — | |
| SCHEMBL1309394 | 0.59 | SLC6A4 (0.43) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136850-A1 | MUSCARINIC RECEPTOR AGONITS USEFUL IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | WO | disclosed |