Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622797 | 0.90 | HTR2A (0.34) | HTR2AMAPTMAPK1MEN1KMT2A | |
| SCHEMBL1134460 | 0.88 | — | — | |
| SCHEMBL1134361 | 0.88 | — | — | |
| SCHEMBL13618261 | 0.88 | — | — | |
| SCHEMBL13622851 | 0.81 | HTR2A (0.35) | HTR2AMAPTMAPK1MEN1KMT2A | |
| SCHEMBL13622803 | 0.73 | MEN1 (0.32) | HTR2AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13631263 | 0.73 | THRB (0.43) | ALDH1A1CHRM1 | |
| SCHEMBL6482034 | 0.71 | KMT2A (0.51) | MAPK1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13623043 | 0.70 | UBE2M (0.32) | MAPK1MEN1KMT2AALDH1A1CHRM1 | |
| SCHEMBL13618239 | 0.70 | BCHE (0.31) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136850-A1 | MUSCARINIC RECEPTOR AGONITS USEFUL IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | WO | disclosed |