Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134340 | 0.92 | OPRL1 (0.43) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134343 | 0.92 | OPRL1 (0.43) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134342 | 0.92 | OPRL1 (0.43) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134406 | 0.92 | OPRL1 (0.43) | OPRL1OPRM1OPRK1 | |
| SCHEMBL13618237 | 0.92 | OPRL1 (0.43) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134350 | 0.92 | OPRM1 (0.41) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134375 | 0.92 | OPRM1 (0.41) | OPRL1OPRM1OPRK1 | |
| SCHEMBL13618226 | 0.92 | OPRM1 (0.41) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134376 | 0.92 | OPRM1 (0.41) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134403 | 0.90 | OPRM1 (0.38) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136850-A1 | MUSCARINIC RECEPTOR AGONITS USEFUL IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | WO | disclosed |