Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622687 | 0.88 | MCHR1 (0.52) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL13622943 | 0.79 | MCHR1 (0.51) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL13622946 | 0.78 | MCHR1 (0.55) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL10145116 | 0.73 | MCHR1 (1.00) | MCHR1CYP3A4CYP2C19KCNH2 | |
| SCHEMBL13622711 | 0.73 | MCHR1 (0.41) | MCHR1KCNH2 | |
| Hydrochloric Acid SCHEMBL539843 | 0.73 | MCHR1 (0.98) | MCHR1CYP3A4CYP2C19KCNH2 | |
| SCHEMBL13622680 | 0.70 | MCHR1 (0.48) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL13622868 | 0.70 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL13025198 | 0.68 | MCHR1 (0.77) | MCHR1 | |
| SCHEMBL13622679 | 0.68 | MCHR1 (0.49) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137270-A2 | AZETIDINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-11-12 | — | — | WO | disclosed |