Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622687 | 0.91 | MCHR1 (0.52) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL13622867 | 0.79 | MCHR1 (0.53) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL13622864 | 0.78 | MCHR1 (0.58) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL10144424 | 0.75 | MCHR1 (0.80) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL13622711 | 0.75 | MCHR1 (0.41) | MCHR1 | |
| Hydrochloric Acid SCHEMBL4476432 | 0.74 | MCHR1 (0.79) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL13622943 | 0.73 | MCHR1 (0.51) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL12680011 | 0.73 | MCHR1 (0.72) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL13025487 | 0.73 | MCHR1 (0.82) | MCHR1 | |
| SCHEMBL11423504 | 0.73 | MCHR1 (0.75) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137270-A2 | AZETIDINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-11-12 | — | — | WO | disclosed |