Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 18/20 | 0.57 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255386 | 0.89 | PTGES2 (0.56) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL13623140 | 0.87 | ALOX5AP (0.55) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL1395500 | 0.86 | PTGES2 (0.53) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL23270814 | 0.84 | ALOX5AP (0.73) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL9146239 | 0.84 | ALOX5AP (0.79) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL30181605 | 0.84 | ALOX5AP (0.79) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL30181492 | 0.84 | ALOX5AP (0.73) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL9044184 | 0.83 | PTGES2 (0.78) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL13415383 | 0.83 | PTGES2 (0.67) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 | |
| SCHEMBL12014950 | 0.81 | ALOX5AP (0.58) | ALOX5APPTGES2ALOX5CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772495-B2 | 5-lipoxygenase-activating protein inhibitor | PANMIRA PHARMACEUTICALS, LLC (US) | 2014-07-08 | — | — | US | disclosed |
| US-20090291981-A1 | 5-Lipoxygenase-Activating Protein Inhibitor | AMIRA PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291981-A1 | 5-Lipoxygenase-Activating Protein Inhibitor | ALOX5, LTA4H, ALOX5AP | ALOX5AP 3/4885PTGES2 42/4885ALOX5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.