Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629250 | 1.00 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12629360 | 1.00 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL4294234 | 1.00 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12410348 | 0.99 | CTSK (0.41) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12410343 | 0.95 | CTSK (0.42) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12676608 | 0.95 | CTSK (0.42) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL1127882 | 0.95 | CTSK (0.42) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12629356 | 0.88 | CTSK (0.50) | CTSKCTSSBIRC2 | |
| SCHEMBL1117254 | 0.87 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL1117169 | 0.87 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141079-A1 | NOVEL [F-18]-LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (II), USE THEREOF AND METHOD FOR THEIR PRODUCTION | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2123619-A1 | New [F-18]-marked L-glutamic acids and L-glutamic acid derivatives (II), application thereof and method for their manufacture | Bayer Schering Pharma AG (DE) | 2009-11-25 | — | — | EP | disclosed |